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Environmental Influences Active and passive smoke exposure Perhaps the single most consistently shown environmental effect on age at menopause is that women who smoke stop menstruating 1 to 2 years earlier than comparable nonsmokers. Enhanced drug metabolism in cigarette smokers. Chronic poisoning of the ovaries and testes of albino rats and mice by nicotine and cigarette smoke. The menopause and climacteric: She has been giving it a lot of thought and is too afraid to show all. Early menopause, number of reproductive years, and bone mineral density in postmenopausal women.
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